Generic Name: Allupurinol (al oh PURE i nole)
Brand Names: Zyloprim
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What is Allupurinol?
• Allupurinol reduces the production of uric acid in your body.
• Allupurinol is used to treat gout, increased levels of uric acid caused by cancer treatment, and kidney stones that are caused by high levels of uric acid.
• Allupurinol may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about Allupurinol?
• To reduce the risk that kidney stones will form, drink 8 to 10 full glasses (8-ounce glasses) of fluid every day, unless your doctor directs otherwise.
• Avoid alcohol. It may worsen your condition.
• Use caution when driving, operating machinery, or performing other hazardous activities. Allupurinol may cause drowsiness. If you experience drowsiness, avoid these activities.
How should I take Allupurinol?
• Take Allupurinol exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water. Also, to reduce the risk that kidney stones will form, drink 8 to 10 full glasses (8-ounce glasses) of fluid every day, unless your doctor directs otherwise.
• Take Allupurinol with food or milk to lessen stomach upset.
• Store Allupurinol at room temperature away from moisture and heat.
What should I discuss with my healthcare provider before taking Allupurinol?
• Before taking Allupurinol, tell your doctor if you have kidney or liver disease. You may need a lower dose of Allupurinol or special monitoring during your therapy.
• Allupurinol is in the FDA pregnancy category C. This means that it is not known whether Allupurinol will harm an unborn baby. Do not take Allupurinol without first talking to your doctor if you are pregnant.
• Allupurinol passes into breast milk. Do not take Allupurinol without first talking to your doctor if you are breast-feeding a baby.
What happens if I miss a dose?
• Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.
What should I avoid while taking Allupurinol?
• Use caution when driving, operating machinery, or performing other hazardous activities. Allupurinol may cause drowsiness. If you experience drowsiness, avoid these activities.
• Avoid alcohol. It may worsen your condition.
• Follow your doctor's recommendations about diet.
What happens if I overdose?
• Seek emergency medical attention.
• Symptoms of an Allupurinol overdose are not known.
What are the possible side effects of Allupurinol?
• If you experience any of the following serious side effects, stop taking Allupurinol and seek emergency medical attention:
· an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
· blood in your urine or pain when you urinate;
· a rash;
· eye irritation;
· fever, chills, or joint aches; or
· severe nausea or vomiting.
• Other, less serious side effects may be more likely to occur. Continue to take Allupurinol and talk to your doctor if you experience
· upset stomach or diarrhea;
· headache, dizziness, or drowsiness; or
· an acute attack of gouty arthritis.
• Side effects other than those listed here may also occur. Talk to your doctor about any reaction that seems unusual or that is especially bothersome.
Where can I get more information?
• Your pharmacist has more information about Allupurinol written for health professionals that you may read.
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